A lesionectomy is an operation to remove a lesion a damaged or abnormally functioning area in the brain. Brain lesions include tumors, scars from a head injury or infection, abnormal blood vessels, hematomas (a swollen area filled with blood), and congenital malformations (brain malformations at birth). A lesion seems to cause seizures in about 20% to 30% of people with epilepsy who do not improve after taking medication; it is not known for certain if the lesion itself triggers the seizures, or if the seizures result from irritation to the brain tissue surrounding the lesion. For this reason, surgery may also include the removal of a small rim of brain tissue around the lesion, called lesionectomy plus corticectomy. Lesionectomy may be an option for people whose epilepsy is linked to a defined lesion and whose seizures are not controlled by medication.
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